In systems with several effectors, the results of dose-response (DR) experiments are usually assessed by checking them against two hypotheses: independent action (IA) and concentration addition (CA).Both are useful simplifications, but do not represent the only possible responses, and avoid to a large extent the analysis of the interactions that ar
The continued development of intraocular lens (IOL) technology has led to a dramatic improvement in refractive outcomes.New and innovative ways of achieving the desired postoperative refractive goals continue to be developed.This article aims to review the currently available IOL modalities for correction of presbyopia at the time of cataract surge
Abstract Background Small-animal PET imaging is an important tool in preclinical oncology.This study evaluated the ability of a clinical SiPM-PET camera to image several rats simultaneously and to perform quantification data analysis.Methods Intrinsic spatial resolution was measured using 18F line sources, and image quality was assessed using a NEM
Abstract Given that hypoxia is a persistent physiological feature of many different solid tumors and a key driver for cancer malignancy, it is thought to be a major target in cancer treatment recently.Tumor-associated macrophages (TAMs) are the most abundant immune cells in the tumor microenvironment (TME), which have a large impact on tumor develo
Managed care may improve access to health care to previously underserved populations when providers need plan enrollees.However, capitation and utilization bml basic management often give providers the incentive to withhold care.Managed care organizations have yet to demonstrate that racial disparities in treatment are not exacerbated.Using Medicai